α-Cyclodextrin (α-CD)
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Structure
6 glucose units linked by α-1,4 bonds (CGTase-processed starch)
Advantages
• Smaller cavity vs β-CD → better stabilizes small molecules
• Higher solubility (14.5g/100mL, 25°C) → ideal for soluble formulations
Quality Standard
| CAS No | Abbreviation |
| 10016-20-3 | ACD |
| Grade | Molecular Formula |
| Food Grade | C₃₆H₆₀O₃₀ |
| Molecular Weight | Appearance |
| 972.84 | White to off-white amorphous or crystalline powder |
| Solubility | Optical Rotation |
| • Freely soluble in water and propylene glycol • Practically insoluble in ethanol and dichloromethane | +147° to +152° |
| Solution Clarity | Assay |
| Clear (10 mg/mL aqueous solution) | 98.0%-101.0% |
| Reducing Sugars | Water Content |
| ≤0.2% | ≤11.0% |
| pH Value | Absorbance of Impurities |
| 5.0-8.0 | • ≤0.10 (230-350 nm) • ≤0.05 (350-750 nm) |
| Microbial Limits | Packaging |
| • Total Aerobic Count: ≤1000 CFU/g • Yeast & Mold: ≤100 CFU/g | • Specification: 20 kg/bag • Material: White paper-plastic composite bag |